Melanotan II

What is Melanotan II (10mg)?

Melanotan II is a laboratory-synthesized alpha-melanocyte-stimulating hormone (α-MSH) mimetic. Structurally modified from the native peptide sequence, its cyclic design dramatically enhances resistance to enzymatic breakdown and increases its biological half-life.

By binding directly to melanocortin receptors, MT-2 triggers a signaling cascade that upregulates the synthesis of eumelanin (the dark brown/black pigment responsible for skin and hair coloration) within melanocytes. Beyond pigmentation pathways, its multi-receptor affinity makes it a primary subject of study in energy homeostasis, sexual function biology, and central nervous system signaling mechanisms.

Key Scientific Applications & Research Benefits

In photobiological, metabolic, and neurological research frameworks, Melanotan II is heavily evaluated for its distinct physiological mechanisms:

1. Acceleration of Melanin Synthesis (Melanogenesis)

Melanotan II mimics native α-MSH by binding strongly to the Melanocortin 1 Receptor (MC1R). This activation boosts the enzymatic activity of tyrosinase, the rate-limiting enzyme in melanin production. Researchers evaluate this mechanism to understand accelerated pigmentation timelines independent of direct, prolonged UV exposure.

2. Photoprotection and UV Damage Mitigation Studies

Eumelanin serves as a natural biological shield against ultraviolet radiation by dissipating harmful UV rays as heat. MT-2 is widely utilized in cellular research to analyze how increased baseline eumelanin density protects epidermal DNA from oxidative stress, mutation, and long-term photodynamic cell damage.

3. Appetite Regulation and Metabolic Axis Evaluation

By interacting directly with Melanocortin 3 and 4 Receptors (MC3R/MC4R) in the hypothalamus, Melanotan II influences systemic energy balance signaling. Scientific literature notes its role in downregulating appetite pathways and activating lipolytic processes, offering key data for metabolic disorder studies.

4. Neurogenic and Libido Pathway Mapping

Activation of central nervous system melanocortin receptors by MT-2 has been documented to modulate autonomic neural pathways. Researchers observe these interactions to study its distinct physiological effects on sexual arousal mechanisms and peripheral erectile function responses.

Technical Specifications & Chemical Profile

Every 10mg vial is subject to rigorous analytical verification to maintain baseline chemical reproducibility:

• CAS Number: 121062-08-6
• Molecular Formula: C50H69N15O9
• Molecular Weight: 1024.18 g/mol
• Purity Profile: ≥98% via High-Performance Liquid Chromatography (HPLC)
• Storage Protocols: Lyophilized powder maintains structural stability at room temperature for up to 90 days. For long-term preservation, store at -20°C. Following reconstitution with bacteriostatic water, preserve tightly refrigerated at 2°C–8°C and use within 20–30 days to protect against active compound degradation.

Disclaimer: This product is synthesized and distributed strictly for laboratory research, in vitro diagnostic profiling, and chemical analysis. It is not approved or intended for direct human therapeutic use, cosmetic application, or consumer ingestion.